titanium dioxide for rubber

One common method to determine sulfate as TiO2 involves gravimetric analysis. In this technique, a sample containing sulfate is treated with barium chloride, resulting in the precipitation of barium sulfate. The precipitate is then filtered, dried, and weighed. The weight of the barium sulfate precipitate correlates directly with the amount of sulfate originally present in the sample. To express this as TiO2, a conversion factor based on stoichiometry is applied. This method, while straightforward, can be time-consuming and subject to errors in filtration and drying.

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In a 2016 study published in Scientifica (Cairo), Egyptian researchers examined the effects of titanium dioxide nanoparticles on the organs of mice by orally administering the food additive daily, for five days. The results showed that the exposure produced “mild to moderate changes in the cytoarchitecture of brain tissue in a time dependent manner.” Furthermore, “Comet assay revealed the apoptotic DNA fragmentation, while PCR-SSCP pattern and direct sequencing showed point mutation of Presenilin 1 gene at exon 5, gene linked to inherited forms of Alzheimer’s disease.” The researchers wrote: “From these findings, “the present study concluded that TiO2NPs is genotoxic and mutagenic to brain tissue which in turn might lead to Alzheimer’s disease incidence.”

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